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Lymphoma

Lymphoma is a type of blood cancer which develops in the lymphatic system, an important part of the immune system.

Jump to: Quick facts Types of lymphoma Signs and symptoms Stages Treatment FAQs

Quick facts about lymphoma

  • Lymphoma is a type of blood cancer which develops in a type of white blood cell known as a lymphocyte

  • Despite its name, lymphoma may also develop in areas other than lymph nodes

  • Over 14,000 people are diagnosed with lymphoma each year in the UK, making it the most common blood cancer.

Types of lymphoma

There are two different types of lymphoma:

  • Non-Hodgkin lymphoma (NHL)

    Non-Hodgkin lymphoma is caused by changes to B-cell and T-cell lymphocytes and is the most common type of blood cancer.  There are many different subtypes of non-Hodgkin lymphoma which are divided into ‘B-cell’ or ‘T-cell’ lymphomas. These abnormal cells eventually become tumours that commonly form in the lymph nodes.

  • Hodgkin lymphoma (HL)

    Hodgkin lymphoma is a rarer type of lymphoma, accounting for less than 1% of lymphoma cases. Unlike non-Hodgkin lymphoma, abnormal B-cell lymphocytes known as Reed-Sternberg cells are present in Hodgkin lymphoma. The cancer is usually found at an early stage and typically spreads through the lymph nodes.

Signs and symptoms of lymphoma

As signs and symptoms for lymphoma can be similar to other common conditions, it’s important to see your GP or healthcare professional if you experience any of the symptoms below. Discussing anything concerning with your doctor as soon as possible can help give you peace of mind and offer the best chance of successful treatment if you receive a lymphoma diagnosis.

Symptoms may include:

Night sweats

Tiredness

Itchy skin

Loss of weight and appetite

Swollen, painless lymph nodes under the arms, neck or groin

Fever

Pain in the chest, coughing and/or trouble breathing

Chronic infection

Enlarged stomach due to swollen lymph nodes or spleen

Stages of lymphoma cancer

The most common system used to stage lymphoma is the Ann Arbour staging system, which helps doctors understand what your cancer looks like.

This staging system uses information such as the number of lymph node groups affected to determine the stage of your lymphoma using the guidelines below:

  • Stage I

    Cancer cells have been found in only one group of lymph nodes.

    Stage 1 lymphoma illustration

  • Stage II

    Two or more lymph node groups have been affected which are localised to either the top or bottom half of the body.

    Stage II lymphoma illustration

  • Stage III

    Two or more lymph node groups have been affected in both sides of the body.

    Stage III lymphoma illustration

  • Stage IV

    Lymph node groups are affected as well as one or more organs, such as your bone marrow or liver.

    Stage IV lymphoma illustration

Treatment for lymphoma

There are many different types of treatment for lymphoma. Your treatment will depend on you and your cancer.

Frequently asked questions about lymphoma

Helpful Links

Lymphoma - what is it, symptoms and treatment | Blood Cancer UK

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