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Cervical Cancer

Cervical cancer is a type of cancer that develops when abnormal cells grow in the tissues of the cervix.

Jump to: Quick facts Types of cervical cancer Signs & symptoms Stages Treatment FAQs

Quick facts about cervical cancer

  • Cervical cancer is the 14th most common cancer in females in the UK, accounting for 2% of all new cancer cases in females*

Types of cervical cancer

The cervix connects the uterus to the vagina in the female reproductive system.

The surface of the cervix is covered by two types of cells. The cell your cervical cancer develops from determines the type of cervical cancer you have:

  • Squamous cells

    These cells line the outer surface of the cervix (ectocervix). Cancer that develops from squamous cells is known as squamous cell carcinoma and is the most common type of cervical cancer (accounting for 70% of cases).

  • Glandular cells

    These cells line the inner surface of the cervix (cervical canal or endocervix). Cancer of these cells is called adenocarcinoma. Adenocarcinoma is less common (25% of cases) than squamous cell carcinoma.

Other carcinomas

There are also some other rare carcinomas of the cervix, such as small cell carcinomas, cervical sarcoma, clear cell adenocarcinoma and mixed carcinomas (adenosquamous) which contain both squamous and glandular cells.

Signs and symptoms of cervical cancer

As signs and symptoms for cervical cancer can be similar to other common conditions, it’s important to see your GP or healthcare professional if you experience any of the symptoms below. Discussing anything concerning with your doctor as soon as possible can help give you peace of mind and offer the best chance of successful treatment if you receive a cervical cancer diagnosis.

Symptoms include:

Vaginal bleeding between periods

Pain or bleeding during or after sexual intercourse

Changes in vaginal discharge

Menstrual bleeding that is longer or heavier than usual

Vaginal bleeding after menopause

Pelvic pain

Stages of cervical cancer

A cervical screening test can determine if there are any abnormal or cancerous cells in the cervix.

The TNM system is used to stage cervical cancer, and it helps doctors plan your treatment. The TNM stands for:

  • Tumour (T) – The degree to which the tumour has affected other tissue, for example how much of the cervix and surrounding tissue has been affected

  • Nodes (N) – Is a measure of whether lymph nodes have been affected

  • Metastasis (M) – Whether the cancer has spread to other parts of the body

The TNM information, along with other tests, helps determine the stage of your cervical cancer using the classifications below:

  • Stage I

    The cancer is confined to the tissue of the cervix.

    Stage 1 cervical cancer illustration

  • Stage II

    The cancer has spread out of the cervix to the upper two-thirds of the vagina or other tissue next to the cervix.

    Stage II cervical cancer illustration

  • Stage III

    The cancer may also have spread to the pelvic side wall, or the tumour is causing obstruction to the kidney(s). The cancer has spread to the pelvic or abdominal lymph nodes.

    Stage III cervical cancer illustration

  • Stage IVa

    The cancer has spread to surrounding pelvic organs, including the bladder or rectum.

    Stage IVa cervical cancer illustration

  • Stage IVb

    The cancer has spread to beyond the pelvis, such as to the lungs, liver or bones.

    Stage IVb cervical cancer illustration

Treatment for cervical cancer

There are many different types of treatment for cervical cancer. Your treatment will depend on you and your cancer.

Frequently asked questions about cervical cancer

Helpful resources

Cervical cancer statistics | Cancer Research UK

Learn more

Cervical cancer | World Health Organization

Learn more

The universal HPV immunisation programme | NHS

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