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Kidney Cancer

Kidney cancer refers to cancer that develops within the kidney.

Jump to: Quick facts Types of kidney cancer Signs and symptoms Stages Treatment FAQs

Quick facts about kidney cancer

  • Each year over 12,500 people in the UK are diagnosed with kidney cancer.

  • Kidney cancer usually only affects one kidney. It is very uncommon for cancer to be in both kidneys. There are different types of kidney cancer.

  • About 8 out of 10 kidney cancers (80%) are renal cell cancers (RCC).

Types of kidney cancer

The kidney plays an important role in removing excess water, salt and waste products from the blood which then becomes urine, and helps control certain processes in the body such blood pressure.

Types of kidney cancer include:

  • Renal cell carcinoma

    Renal cell carcinoma is a cancer that develops in the kidney’s filtration system (proximal renal tubules). This is the most common type of kidney cancer, accounting for 80% of all kidney cancer diagnoses.

  • Urothelial carcinoma

    Urothelial carcinoma is a cancer that develops in the transitional cells which line the renal pelvis (where the ureters meet the kidneys). This accounts for 20% of all kidney cancer cases and includes Hürthle cell carcinoma.

  • Wilms tumour

    This is a rare cancer that develops in the kidneys from the abnormal growth of early kidney cells, most commonly in children.

  • Renal sarcoma

    Renal sarcoma is a rare cancer that develops in the connective tissue or blood vessels of the kidney. This accounts for less than 1% of all kidney cancer diagnoses.

Signs and symptoms of kidney cancer

As signs and symptoms for kidney cancer can be similar to other common conditions, it’s important to see your GP or healthcare professional if you experience any of the symptoms below. Discussing anything concerning with your doctor as soon as possible can help give you peace of mind and offer the best chance of successful treatment if you receive a kidney cancer diagnosis.

Kidney cancer can be difficult to detect as there are often no symptoms during the early stages. However, as the disease progresses, symptoms may include:

Blood in urine

Pain or discomfort in the lower back or side

Unexplained weight loss

Fatigue

A mass or lump in the abdomen

Fever

Stages of kidney cancer

The TNM system is used to stage kidney cancer and helps doctors understand what your cancer looks like. TNM stands for:

  • Tumour – The size of the tumour

  • Node – If the cancer has involved any lymph nodes

  • Metastasis – Whether the cancer has metastasised (spread) to other areas of the body.

The TNM information, along with other tests, helps determine the stage of your breast cancer using the guidelines below:

  • Stage I

    The cancer is no larger than 7cm across and confined to the kidney.

    Stage 1 kidney cancer illustration

  • Stage II

    The cancer is larger than 7cm across and confined to the kidney.

    Stage II kidney cancer illustration

  • Stage III

    The cancer has grown into a major vein or surrounding tissue, but not the adrenal gland or beyond Gerota’s fascia. Alternatively, the tumour is any size and has spread the nearby lymph nodes but not beyond Gerota’s fascia.

    Stage III kidney cancer illustration

  • Stage IV

    The cancer has grown beyond Gerota’s fascia and may be growing into the adrenal gland. It may or may not have spread to nearby lymph nodes. Alternatively, the cancer has spread to distant lymph nodes and/or organs.

    Stage IV kidney cancer illustration

Treatment for kidney cancer

There are many different types of treatment for kidney cancer. Your treatment will depend on you and your cancer.

Frequently asked questions about kidney cancer

Helpful links

Kidney cancer statistics | Cancer Research UK

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Incidence of kidney cancer in the UK | Kidney Cancer UK

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Kidney cancer | Macmillan Cancer Support

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